Specimen Requirements

Title

TRAZODONE (DESYREL)

Specimen Requirement

1 Red Top/2.0 mL serum. Do not collect in serum separator tube. After 30 minutes of clotting, promptly centrifuge, separate and refrigerate serum.

Methodology

Stability

Room Temperature 48 hours, Refrigerated 14 days, Frozen 14 days

Reference Range

By Report*

Turnaround

2-3 days Performed Mon, Wed, Fri

Clinical Use

For therapeutic drug monitoring of antidepressant therapy. Peak plasma levels occur approximately 1 hour after dosing when Trazodone is taken on an empty stomach or 2 hours after dosing when taken with food. Elimination of Trazodone is biphasic, consisting of an initial phase (half-life 3-6 hours) followed by a slower phase (half-life 5-9 hours).

Test Code

TRAZO