Specimen Requirements
Title
TRAZODONE (DESYREL)
Specimen Requirement
1 Red Top/2.0 mL serum. Do not collect in serum separator tube. After 30 minutes of clotting, promptly centrifuge, separate and refrigerate serum.
Methodology
Stability
Room Temperature 48 hours, Refrigerated 14 days, Frozen 14 days
Reference Range
By Report*
Turnaround
2-3 days Performed Mon, Wed, Fri
Clinical Use
For therapeutic drug monitoring of antidepressant therapy. Peak plasma levels occur approximately 1 hour after dosing when Trazodone is taken on an empty stomach or 2 hours after dosing when taken with food. Elimination of Trazodone is biphasic, consisting of an initial phase (half-life 3-6 hours) followed by a slower phase (half-life 5-9 hours).
Test Code
TRAZO