Specimen Requirements

Title

Protein Electrophoresis, Urine Random

Specimen Requirement

Collect first morning urine, mix well, send 12 mL (minimum 6 mL) urine in a sterile container.

Do not use preservative.

Methodology

Electrophoresis on agarose media

Stability

Room temp: 14 days, Refrigerated: 14 days, Frozen: 14 days

Reference Range

The reference range is determined by the performing laboratory and will show on the report.

Turnaround

3-5 days

Clinical Use

Evaluate myeloma, macroglobulinemia of Waldenström, lymphoma, amyloidosis; differentiate between normal renal function, glomerular proteinuria, and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight problems.

Test Code

UPEMC