Specimen Requirements

Title

PROINSULIN

Specimen Requirement

Patient must fast 12-15 hours before collection.

Draw blood in a SST/1.0 mL serum. Spin, separate serum from cells within 2 hours and send refrigerated.

Methodology

Stability

Room Temperature Unacceptable, Refrigerated 7 days Frozen 3 months

Reference Range

By Report*

Turnaround

3-7 days Performed Tues, Thurs

Clinical Use

To aid in the diagnosis of pancreatic beta cell dysfunction and proinsulinomas. Increased in IDDM and may also be increased in NIDDM patients. Levels are elevated in older patients, pregnant or obese diabetics, patients with functional hypoglycemia, insulinoma and hyperproinsulinoma.

Test Code

PINS