Specimen Requirements


Porphobilinogen, Random Urine

Specimen Requirement

Collect 2.0 mL random urine in a sterile container, protect from light and send refrigerated.

Proctect from light.


Chromatography/Mass Spectrometry


Room temp: Unacceptable, Refrigerated: 7 days, Frozen: 30 days

Reference Range

Reference ranges are determined by the performing laboratory and will show on the report


5-8 days Performed Tuesday, Thursday, Saturday

Clinical Use

Detect porphyrias and porphyrinurias. Acute intermittent porphyria is characterized by excretion of porphobilinogen and delta aminolevulinic acid in urine during acute attacks, but not during latency. Increased porphobilinogen may be caused also by variegate porphyria or hereditary coproporphyria. Increased urine values are seen in the intoxication porphyrias (heavy metals, halogenated solvents, certain drugs).

Test Code