Specimen Requirements

Title

LIVER-KIDNEY MICROSOMAL ANTIBODY

Specimen Requirement

1 SST/1.0 mL serum. After 30 minutes of clotting, promptly centrifuge and refrigerate.

Methodology

Stability

Refrigerated 21 days, Frozen 30 days

Reference Range

By Report*

Turnaround

4-DAYS --PERFORMED TUES,THURS,FRI

Clinical Use

The detection of LKM-1 Antibodies is an aid in the diagnosis of autoimmune hepatitis, type 2 (AIH2). LKM Antibodies are markers of AIH2 which usually begins in childhood and generally affects children under 18 years of age. LKM antibodies are associated with a more serious progression of the disease. The disease is most common between the ages of 2-14 and is more frequent in females than males (8:1). LKM-1 antibodies have been reported in up to 8% of patients with chronic HCV infection.

Test Code

LKMW