Specimen Requirements

Title

JAK2 Exon 12, 13, 14 and 15 Mutation Analysis by NGS

Specimen Requirement

Collect lavender EDTA, green sodium heparin or yellow ACD/3.0 mL whole blood, send whole blood room temperature to the lab same day.

Alternate collection: 1 mL bone marrow

Methodology

Amplicon-based Next Generation Sequencing

Stability

Room temp: 48 hours, Refrigerated/Frozen: Unacceptable

Reference Range

Reference ranges are determined by the performing laboratory and will show on the report.

Turnaround

7 days

Clinical Use

Molecular testing of blood or bone marrow is useful in the evaluation of suspected myeloproliferative neoplasms (MPN). This test will assess mutations in JAK2 exons 12, 13, 14 and 15.

Test Code

JAKLC