Specimen Requirements
Title
Intrinsic Factor Blocking, AB
Specimen Requirement
DRAW BLOOD IN A SST/1.0 mL. SPIN, SEPARATE SERUM FROM CELLS WITHIN 2 HOURS.
VERY HIGH SERUM LEVELS OF VITAMIN B12 MAY GIVE FALSE POSITIVE RESULTS FOR INTRINSIC FACTOR ANTIBODY. NO SAMPLE SHOULD BE COLLECTED FROM A PATIENT WHO HAS RECEIVED VITAMIN B12 INJECTION WITHIN THE PAST WEEK.
Methodology
Stability
Room Temperature 8 Hours; Refrigerated 48 Hours
Reference Range
By Report*
Turnaround
3-5 days
Clinical Use
Differentiation of pernicious anemia from other megaloblastic anemias. Intrinsic factor blocking autoantibodies are found in approximately 75% of patients with pernicious anemia. High serum concentrations of vitamin B12 (cobalamin) cause false positive results.
Test Code
IFA