Specimen Requirements
Title
IA2 Autoantibodies
Specimen Requirement
Collect SST/1.0 mL serum allow to clot for 30 minutes, centrifuge and send.
Methodology
Enzyme-linked Immunosorbent Assay (ELISA)
Stability
Room temp: 3 days, Refrigerated: 3 days, Frozen: 14 days
Reference Range
The reference range is determined by the performing laboratory and will show on the report.
Turnaround
5-10 days
Clinical Use
Type 1 diabetes, commonly referred to as insulin-dependent diabetes (IDDM), is caused by pancreatic beta-cell destruction that leads to an absolute insulin deficiency. The clinical onset of diabetes does not occur until 80% to 90% of these cells have been destroyed. Prior to clinical onset, type 1 diabetes is often characterized by circulating autoantibodies against a variety of islet cell antigens, including glutamic acid decarboxylase (GAD), tyrosine phosphatase (IA2),
Test Code
IA2A