Specimen Requirements
Title
HIV-1 Genotype
Specimen Requirement
Collect PPT/2.0 mL plasma, centrifuge and send.
Alternate sample: Lavender EDTA, centrifuge, pipette 2.0 mL plasma to a screw top transport tube, indicate sample type on tube and send.
Methodology
DNA Sequencing • Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)
Stability
Room temp: 24 hours, Refrigerated: 6 days, Frozen: 42 days
Reference Range
By Report*
Turnaround
4-9 days
Clinical Use
This test is intended for use in conjunction with clinical presentation and other laboratory markers of disease progress for the clinical management of HIV-1 infected patients. The test identifies drug resistance-associated mutations in the HIV-1 protease and reverse transcriptase genes. It can be used to predict antiretroviral drug resistance before initiation of therapy and in patients experiencing virologic failure while on therapy.
Test Code
GTHIV