Specimen Requirements

Title

ANTI-SMOOTH MUSCLE ANTIBODIES

Specimen Requirement

1 SST/1.0 mL serum. After 30 minutes of clotting, promptly centrifuge and refrigerate.

Methodology

Stability

Room Temperature 8 hours, Refrigerated 48 hours, Frozen 14 days

Reference Range

By Report*

Turnaround

2 days Performed Mon-Fri

Clinical Use

Useful in the diagnosis of liver disease. High titers of SMA of antiactive specificities are found in 97% of patients with autoimmune chronic active hepatitis. SMA (non-anti- active) are also found in virus induced liver disease. Absence of SMA and nuclear antibodies argues for non-autoimmune forms of chronic hepatitis

Test Code

ASMW