Specimen Requirements
Title
TMAO (Trimethylamine N-oxide)
Specimen Requirement
Collect plain red top tube, gently invert 5 times (do not shake). Allow specimen to clot completely (about 30 minutes), centrifuge and transfer 1 mL serum to a screw top plastic vial, indicate serum on the tube and send.
Patient Preparation:
Patient should fast for 10-12 hours and avoid consuming fish the day prior to collection.
Methodology
Nuclear magnetic resonance (NMR)
Stability
Room temp: 14 days, Refrigerated: 14 days, Frozen: 14 days
Reference Range
The reference range is determined by the performing laboratory and will show on the report.
Turnaround
3-5 days
Clinical Use
The TMAO test may be used as an aid in the assessment of risk for cardiovascular disease (CVD), independent of established risk factors, an aid in the determination of altered gut microbiome (gut dysbiosis) in individuals who may benefit from intensive dietary intervention, and a monitor therapy aimed at reducing TMAO concentrations.
Test Code
TMAO