Specimen Requirements
Title
Oxcarbazepine (10-Hydroxy Carbazepine) (Trileptal)
Specimen Requirement
Collect plain red top or lavender EDTA, centrifuge, transfer 1.0 mL serum/plasma to as crew top plastic vial, indicate sample type on tube and send.
Do not use a gel-barrier tube.
Draw trough levels immediately prior to next dose. Steady-state levels are reached within two to three days in patients taking oxcarbazepine twice daily.
Methodology
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Stability
Room temp: 14 days, Refrigerated: 14 days, Frozen: 14 days
Reference Range
The reference range is determined by the performing laboratory and will show on the report.
Turnaround
2-4 days
Clinical Use
Oxcarbazepine is an antiepileptic drug, indicated for use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults with epilepsy. It is used in adjunctive therapy in epileptic children between the ages of four and 16.
Test Code
OXC