Specimen Requirements

Title

Methylmalonic Acid, Serum

Specimen Requirement

Collect SST/2.0 mL serum, allow to clot for 30 minutes, promptly centrifuge and send.

Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Stability

Room temp: 14 days, Refrigerated: 14 days, Frozen: 19 days

Reference Range

The reference range is determined by the performing laboratory and will show on the report.

Turnaround

3-6 days

Clinical Use

Serum methylmalonic acid (MMA) measurement is used to evaluate individuals with signs and symptoms associated with vitamin B12 deficiency or congenital methylmalonic academia.

Test Code

MMA/A