Specimen Requirements

Title

DNA (ss) ANTIBODY, lgG

Specimen Requirement

Methodology

Enzyme Immunoassay

Stability

Room Temp: 1 week; Refrigerated: 2 weeks; Frozen 2 months

Reference Range

Not detected: <68.6 units/mL
Moderately positive: 68.6-229 units/mL
Strongly positive: >229 units/mL

Turnaround

5-7 days

Clinical Use

Single-stranded DNA (ssDNA) autoantibodies are found in 80-90% of SLE patients during the administration of certain drugs (e.g., procainamide or quinidine) and other autoimmune diseases including rheumatoid arthritis, scleroderma, linear localized scleroderma, polymyositis- polymyositis-dermatomyositis, Sjogren syndrome, mixed connective tissue disease (MCTD) and overlap syndromes, myasthenia gravis, chronic active hepatitis, infectious mononucleosis, chronic glomerulonephritis, and biliary cirrhosis.

Test Code

1117